New Jersey State Police officials said the crash was reported at 1:46 a.m. Thursday west at Milepost 39.4 in Winslow Twp.
A preliminary investigation indicated that a Honda Accord traveling eastbound struck a deer, went off the road to the left into the center median, and entered the westbound lanes where it struck a GMC Acadia.
According to NJ State Police, the driver of the Honda, Ms. Emily Fitzpatrick, 27, of Hammonton, sustained fatal injuries.
The driver of the GMC was not injured.
The westbound lanes were closed for approximately two hours.